Whether mild or severe, if you suffer from dry eye syndrome, you will know the importance of having a reliable bottle of eye drops on hand at all times. Dry eyes can cause serious irritation, which is why there are so many brands catering for this aggravating condition, with many of them formulated for contact lenses and preservative-free alternatives too.
Brands like Optrex and Murine have some inexpensive options for milder conditions, while Artelac and Ocusan are leading the way in stronger eye drops for more severe cases. We've collected a healthy top 10 from the reliable likes of Amazon, Boots, Waitrose and Tesco to make certain there won't be a single dry eye in the house!
Quick List - Top Eye Drops for Dry Eyes
Hycosan Extra
High Strength Non-prescription Eye Drops for Treating Severe Symptoms
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The first question to ask when looking for eye drops is, "Are they suitable for my eyes?". Although easy to ask, this can sometimes be a complicated question to answer. This is because we all have varying levels of dry eye and many brands have their own take on certain formulas, so it can sometimes seem tricky to figure out.
That's why, first and foremost, you should know that most eye drops will either be recommended for mild cases of dry eyes or for moderate-to-severe cases. It will usually be stated on the label, but the actual factors that dictate this are all in this guide.
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Sodium hyaluronate is the magic ingredient in just about every eye drop formula, as it has excellent moistening properties that mimic the body's own tear fluid. Found in various connective tissues of the human body, sodium hyaluronate is a naturally-occurring mineral and therefore is more than safe to drop into the eyes.
Eye drops have varying sodium hyaluronate content which indicates its strength, and the severity of dryness they are recommended for. Over-the-counter drops usually have between 0.1 and 0.25 % of sodium hyaluronate, with 0.1% recommended for milder cases and 0.2% for moderate-to-severe cases. Some can have up to 0.4% sodium hyaluronate, however, these aren't widely available without a prescription.
Preservatives are chemicals added to eye drop formulas to stave off the growth of bacteria within a bottle once it's opened, extending its shelf life. These eye drops come in multi-drop bottles that can often be used for up to six months after opening.
Eye drops with preservatives are only recommended if you have a mild case of dry eyes. If you are using eye drops for dry eyes no more than four to six times a day, then the preservatives should have little to no effect on your eyes. On the other hand, if you are using them more than four to six times a day, doctors recommend the use of preservative-free eye drops.
Although many eye drops for severe dry eyes will require a prescription, you can find OTC preservative-free eye drops online. They are recommended for people with medium-to-severe cases of dry eyes because they eliminate the risk of further irritation to the eye.
Unlike eye drops with preservatives, preservative-free drops can be used as many times as you like each and every day. This makes them the perfect little eye drop companions for instant relief. The only drawback of being preservative-free is that these drops are often more expensive than their preservative-included counterparts.
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Single-dose eye drops have the exact same formula, the only difference is that they come in tiny plastic vials instead of multi-dose bottles. These are most common in preservative-free drops where the potential for bacteria growth within the bottle increases.
You will find them in multipacks of between 20 and 30, with each vial having between 0.04 and 0.05 ml – the amount required for one dose in both eyes – but you can always stock up with a bulk buy if needed. Just be aware that this increased packaging coupled with the preservative-free formula ultimately entails a further increase in price per 10 ml.
Thankfully, many of the market-leading eye drops for dry eyes are compatible with contact lenses. However, it's still always worth double-checking as the more budget brands will not state whether or not they are contact lens-friendly, making rolling the dice with these drops fairly risky.
If you wear contacts regularly, then the safest option is to look out for eye drop brands that focus even more attention on creating a formula designed for use with lenses. For example, you could look for claims of suitability with both soft and hard contact lenses.
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Products | Image | Click to purchase | Key features | |
---|---|---|---|---|
1 | Artelac Every Day Eye Drops | ![]() | Unbeatable Quality Eye Drops With High 0.24% Sodium Hyaluronate Content | |
2 | Ocusan Single Dose Eye Drops for Dry Eyes | ![]() | Single Dose Eye Drops for Extremely Dry Eye | |
3 | Hycosan Extra Preservative-Free Eye Drops | ![]() | High Strength Non-prescription Eye Drops for Treating Severe Symptoms | |
4 | Thealoz Duo Eye Drops | ![]() | Dry Eye Drops With 3% Trehalose to Help Protect Corneal Cells | |
5 | Murine Dry & Tired Eye Drops | ![]() | 8 Hour Relief for Dry and Tired Eyes | |
6 | Optrex Intensive Eye Drops | ![]() | Lubricating Drops for Dryness Caused by Environmental Stress | |
7 | Systane Ultra Lubricant Eye Drops | ![]() | Sodium Hyaluronate-Free Drops for Use With Hard and Soft Contact Lenses | |
8 | Vizulize Lubricating Dry Eye Drops | ![]() | Contact Lens-Friendly Moisturising Drops for Mild Dry Eyes | |
9 | Boots Preservative-Free Single Dose Drops | ![]() | Single Dose Eye Drops for Mild Allergies and Irritation | |
10 | Blink Intensive Tears Vials | ![]() | Inexpensive Drops for Moderate-to-Severe Dryness |
Artelac's everyday drops for fast and lasting dry eye relief are designed for persistent moderate-to-severe cases, whether from screen use, tiredness, contacts or your environment. With a sodium hyaluronate content of 0.24%, they are the strongest drops on this list.
This high sodium hyaluronate content coupled with being preservative-free and contact lens-friendly makes it easy to see why these drops take our top spot. With tonnes of happy reviewers on Amazon enthusing about the effectiveness of these soothing eye drops, this is a purchase you and your eyes won't regret!
Ocusan is another market-leading eye drop brand with upper-echelon drops for moderate-to-severe cases of dry eye. Included are 20 single-dose vials with 0.5 ml in each vial. This makes for a well-portioned, healthy dose of drops every time you need them.
The single-dose vials also eliminate any risk of bacteria growth tampering with your preservative-free drops. They're even compatible with all types of contact lenses, making for a well-rounded single drop set that's destined to offer relief in even the most stubborn of cases.
These drops are particularly high in the sodium hyaluronate department at 0.2%, making them recommended for more persistent and severe cases of dry eye. Despite this, they're compatible with all types of contact lenses and are also pleasantly preservative-free.
Though they have a higher price and a smaller 7.5 ml bottle, don't be put off, as this is a clear indicator they're top-shelf eye drops of the highest quality. These are really the last defence in the fight to cure your dry eyes before it's time to book an appointment to see the GP.
Though you may notice quite a substantial leap in price, these eye drops from Thealoz boast the unique inclusion of 3% trehalose. Trehalose is a naturally-occurring glucose that's found in all types of plants and animals, which prevents corneal cells from diminishing due to dryness.
Coupled with 0.15% sodium hyaluronate, these duo drops are a supreme team to fight the good fight against dry eyes of all levels. They are also preservative-free and contacts-friendly, making it easy to see why these drops are in the higher threshold for price.
Murine is another brand with plenty of eye drop options available in their range, but we particularly recommend these drops for dry and tired eyes, which are designed to soothe for up to 8 hours at a time. A quick look through the ingredients list shows that there's sodium hyaluronate included but the percentage is not stated.
On account of the low price, high net weight and the inclusion of preservatives, it's more than likely that these drops have 0.1% sodium hyaluronate, though it's not a given. This would make them more suited to mild dry eyes, but for the price, they're still a great deal indeed.
Optrex are a hugely popular eye drop brand with many varieties that are readily available online. This is their intensive formula for dry eyes with a sodium hyaluronate content of 1.5%. This sits right in the middle of drops for mild and severe cases, so they're ideal for easing dryness from computer use, air conditioning, central heating and similar.
Being branded for everyday use, they are also compatible for use with contact lenses, making them a good mid-range in terms of both strength and price. However, with the inclusion of preservatives, it's still good to be cautious if you suffer from a moderate-to-severe case of dry eyes.
Coming highly recommended by Amazon reviewers and doctors alike, the Systane ultra eye drops use glycol instead of sodium hyaluronate to lubricate the eye. People are raving about its almost gel-like consistency that gives instant soothing relief.
They're also perfectly suitable for use with both soft and hard contact lenses. Without the sodium hyaluronate no recommendation has been given to the severity of dry eyes they best suit, but with the inclusion of preservatives it's safe to assume they're for mild cases only.
Vizulize's eye drops for dry eyes give long-lasting relief for people with mild cases of dryness from humid, dry environments and all-day screen use. They are designed to moisturise and soothe dry eyes and are also contact lens-friendly, making them ideal for just about anyone.
Coming in at only a few pounds a bottle also makes them the cheapest drops on this list. The only downside is that they aren't preservative-free. This shouldn't pose a risk to people with mild dry eyes, but it's still something worth noting if you want to use them frequently throughout the day.
These drops from the Boots eye drop range are recommended for dry eyes of all levels. Being cheap, preservative-free, single dose and contact lenses-friendly, they certainly tick many of the eye drop boxes.
However, they don't necessarily excel in other areas. The 0.1% of sodium hyaluronate indicates drops for mild eyes, which is a slight contradiction for the need of preservative-free single-dose drops. Though a slightly confused set of single doses, at least they're cheap!
Blink's intensive eye drops are very much on the budget end for people with moderate-to-severe dry eyes. With a sodium hyaluronate content of 0.20%, it's clear that these drops aren't for mild cases of dryness.
Their biggest downfall is their inclusion of preservatives, which aren't recommended for cases of severe dry eye, so tread lightly initially. On the plus side, the single-dose drops of 20 vials with 0.4 ml make them an ideal amount for both eyes in one session – just make sure not to miss!
Written and researched by Connor Macanally
No. 1: Artelac|Every Day Eye Drops
No. 2: Ocusan|Single Dose Eye Drops for Dry Eyes
No. 3: Hycosan Extra|Preservative-Free Eye Drops
No. 4: Thealoz|Duo Eye Drops
No. 5: Murine|Dry & Tired Eye Drops
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